September 15, 2013

Vitamin D3 May Beat D2 as Supplement

From medpagetoday.com


Vitamin D3 May Beat D2 as Supplement
Published: Sep 4, 2013 | Updated: Sep 5, 2013

"... they concluded that the findings "question the usefulness of vitamin D2 supplements," and suggested that instead, vitamin D3 "should be used for supplementation and fortification purposes."

By Kristina Fiore, Staff Writer, MedPage Today
Reviewed by F. Perry Wilson, MD, MSCE; Instructor of Medicine, Perelman School of Medicine at the University of Pennsylvania and Dorothy Caputo, MA, BSN, RN, Nurse Planner

When it comes to raising a patient's overall vitamin D status, supplementation with vitamin D3 may be more effective than vitamin D2, researchers found.

In a randomized controlled trial, increases in serum 25(OH)D over 8 weeks were significantly greater among patients on vitamin D3 than those taking D2 or placebo, Jutta Dierkes, PhD, of the University of Bergen in Norway, and colleagues reported online in the Journal of Clinical Endocrinology and Metabolism.

And giving vitamin D2 appeared to diminish vitamin D3 levels, they found.

"Our major finding is that vitamin D3 increased 25(OH)D more effectively than vitamin D2," they wrote. "By measuring the specific hydroxylated forms, we have been able to show that the underlying reason for this difference is a substantial decrease in 25(OH)D3 in subjects receiving vitamin D2."

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